Đánh giá tình hình sử dụng kháng sinh thông qua chỉ số ngày điều trị kháng sinh tại Bệnh viện Bệnh Nhiệt đới Thành phố Hồ Chí Minh giai đoạn 2016 – 2018

According to using days of therapy (DOTs), a cross-sectional study was conducted to evaluate the antibacterial use in the Hospital for Tropical Diseases in Ho Chi Minh City in 2 years (01/04/2016 – 31/03/2018). A total of 28.164 medical records (25.468 patients) were reviewed. Most patients (92.05 %) admitted to hospital one-time-only and 49.42 % of patients were children. The number of patients who used one antibiotic accounted for 71.96 %. The most commonly prescribed antibiotic was ceftriaxone (7.756 cases made up 27.54 %), whereas cefotaxime and cefepime were used at least (each drug included 3 cases, comprised 0.01 %). The DOTs per 1000 patient days (DOTs/1000PDs) was 822.14. In the first year of study (04/2016 – 03/2017), the DOTs/1000PDs was 839.46 and decreased by 4.28 % in the second year (04/2017 – 03/2018). There was a slight decline in the slope of the regression line of DOTs/1000PDs with 6.44 (95% confidence interval [6.23 – 6.64]) after one-year implementing Antimicrobial Stewardship Program.
Keyword: Antibiotics, Antimicrobial Stewardship Program, Antibacterial use, Days of Therapy, DOTs, Hospital for Tropical Disease in Ho Chi Minh City